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BeatSIBO

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Is it SIBO, or something that looks like it?

IBS is a diagnosis of exclusion. SIBO is a test result. That difference is why people end up carrying both labels, and why two breath tests can disagree about the same person in the same week.

Start with what you were told you have
One patient, two breath tests
Lactulose
Positive
Glucose
Negative

The ordinary outcome, not a lab error. Where patients took both tests, 74% of overgrowth diagnoses were made by the lactulose test alone.

Why they disagree

Why you should believe any of this

Every source carries a label saying how strong it is, so a preprint never reads like a clinical guideline. Every price shows the date we checked it. Where specialists disagree we say so and name both positions instead of picking the tidier one.

The guideline underneath most of this rates five of its six recommendations as resting on evidence its own authors grade as very low quality. We would rather tell you that than write around it.

How we grade evidenceEverything we got wrong